Phages and Precision Medicine

Bacteriophages target specific bacterial cells and destroy them leaving all other cells unharmed. These organisms have been used for phage therapy - a treatment for disease that involves administering the specific bacteriophage corresponding to a given bacterial infection in order to treat it. Now that the continuous use of broad spectrum antibiotics has resulted in superbugs with high levels of antibiotic resistance, phage therapy might be the precision medicine solution that we need. This will require us to overhaul our current thinking about pharmaceuticals and adopt more localised manufacture.

Predicting the Future

The fictional science of psychohistory is predicated on the proposition that while human behaviour is erratic in isolation, when aggregated to population scale it becomes predictable. Today we use big data to predict customer behaviour and third wave economics uses real-time data to solve real world problems. In time this will allow us to understand the steps we need to take to shape desirable outcomes.

Privacy Self-Management

When there were limited uses to which data could be put, it was easy to evaluate the harms that could result from providing consent. Things are much more complex today so data protection regulations have tried to improve the quality of consent. This has resulted in the transparency paradox. If we can adopt consent templates we can give users appropriate autonomy.

Calculated Communication

Every evolution of communications technology from the printing press to the telegraph to telephones and eventually the internet has placed new and different stresses on personal privacy. As much as we welcome these technologies when launched, in time we realise the effect that they can have on personal privacy. The whole point of communicating is to violate your privacy in a controlled way. But if we do not have information about all the ways in which a given communication can affect your privacy you cannot really exercise effective control over it.

Should AI own IP

The South African patent office has granted a patent to an artificial intelligence program for an invention it has made. India granted a copyright to an AI application along similar lines. It is not clear how an artificial intelligence can exercise the IP granted by prosecuting a breach or negotiating commercial arrangements for its license. All these actions will have to be taken by humans on behalf of the AI in which case what is the point in calling the algorithm an inventor.

Identity and Privacy

Identity is a prerequisite for the provision of services and efficient identity systems are necessary to scale digital public infrastructure. We can build back trust in identity systems through encryption and tokenisation of identity information by using privacy preserving technologies like zero knowledge proofs so that we can still establish eligibility for a service without exposing identity information.

Opening Closed Spaces

The reason why email is the most widely used messaging protocol is because it uses an open interoperable protocol that allows messages to be exchanged freely regardless of the underlying operating system. If we are to take advantage of the benefits of data we need to enable open interoperable protocols that will break down the silos of our digital infrastructure.

The Future of Title

The cutting edge of innovation in NFTs is taking place in the gaming space. Most NFT based games use non-fungible tokens to attest the title of in-game digital assets. If we start to use the metaverse for more and more real world activities, we will need some way to assert title over digital assets. NFT’s could become the future of title in the metaverse.

Unpacking the Retail Stack

In order to extract greater efficiency out of existing systems we sometimes need to break the atomic units of those systems down into even smaller pieces so that we can re-imagine how they can be put back together. This is the sort of unbundling that we need to do of the retail stack in order to be able to build a digital retail infrastructure that can empower our small traders. This is the only way we can enable hyperlocal commerce at national scale.

The App Store Tax

The courts in the US have upheld the App Store model arguing that it demonstrates pro-competitive features that outweigh concerns of monopolistic activity. All it does is prevent operators of these stores from putting in place measures that ensure that all in-app transactions be routed exclusively through the App Store so the fees can be deducted at source.